For those that came to it, there was one Technote which did not make it to the slides as it came out post the freeze date.
It is related to the iNotes reverse proxy which is broken in 8.5.1.
The technote found is #1412267.
My conversations with IBMers found this will be resolved in 8.5.2.
In the meantime you can try this or revert your iNotes server and redirector to 8.5 or earlier.
For all of those who have been asking me what was wrong, this was broken in 8.5.1(some people reported other issues in 8.5 but most of what I hear is about this version.